Metformin Use in High Risk Patients

Metformin may be beneficial for high risk patients

     According to a study in the Archives of Internal Medicine in November 2010, metformin was shown to decrease mortality in patients with pre-existing arterial disease. It decreased the risk of death by 24% in patients with documented cardiac or arterial disease.
The researchers attributed these affects due to metformin’s multiple sites of action, including decreasing insulin resistance, improving lipoprotein levels, and modestly reducing body weight, which are all proven risk factors for cardiovascular related deaths.